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Open Targets Platform Query Skill

技能 已验证 活跃

Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification. Part of the AlterLab Academic Skills suite.

目的

To facilitate therapeutic target identification and assessment by providing structured access to the comprehensive data within the Open Targets Platform.

功能

  • Query target-disease associations
  • Discover potential drug targets
  • Retrieve target tractability and safety data
  • Access genetics and omics evidence
  • Find known drugs and their mechanisms

使用场景

  • Use when identifying potential therapeutic targets for a disease.
  • Use when evaluating the druggability and safety of candidate genes.
  • Use when gathering evidence to support target-disease hypotheses.
  • Use for drug repurposing investigations.

非目标

  • Performing novel biological research outside of data retrieval and analysis.
  • Replacing expert biological interpretation with automated decision-making.
  • Directly interacting with laboratory equipment or experimental design.

工作流

  1. Search for entities (targets, diseases, drugs) by name.
  2. Retrieve detailed information for a specific target, disease, or drug.
  3. Query evidence linking targets to diseases across various data types.
  4. Find known drugs associated with a disease and their development status.
  5. Analyze target associations and their supporting evidence.

实践

  • Drug target discovery
  • Therapeutic hypothesis generation
  • Bioinformatics data analysis

先决条件

  • Python 3.7+
  • requests library (pip install requests)

安装

npx skills add AlterLab-IEU/AlterLab-Academic-Skills

通过 npx 运行 Vercel skills CLI(skills.sh)— 需要本地安装 Node.js,以及至少一个兼容 skills 的智能体(Claude Code、Cursor、Codex 等)。前提是仓库遵循 agentskills.io 格式。

质量评分

已验证
100 /100
1 day ago 分析

信任信号

最近提交17 days ago
星标15
许可证MIT
状态
查看源代码

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